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Month: August 2022
Bempedoic acid is a prodrug metabolized in the liver by very‐long‐chain acyl‐CoA synthetase 1 (ACSVL1) to form the pharmacologically active bempedoyl‐CoA metabolite, which inhibits hepatic cholesterol synthesis and leads to upregulation of hepatic low‐density lipoprotein receptors, increases low‐density lipoprotein uptake and …
